Celox™ granules are actually very high surface area flakes. When they come in contact with blood, Celox™ swells, gels, and sticks together to make a gel like clot.

Celox™ stops bleeding by bonding with red blood cells and gelling with fluids to produce a sticky pseudo clot. This clot sticks well to moist tissue to plug the bleeding site.

Celox™ does not set off the normal clotting cascade, it only clots the blood it comes directly into contact with.

Celox’s™ mode of action has a number of big benefits:

• Celox’s™ clotting ability has been proven to work in the presence of common anti-coagulants such as warfarin …
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• Celox’s™ clotting ability has been proven to work in the presence of heparin
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• Celox’s™ rapidly clots hypothermic (cold) blood
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Celox™ is made with chitosan, a natural polysaccharide. Chitosan has a known metabolic pathway. That means any left in the body is broken down by the bodies normal enzymes and converted into materials normally present in the body.

Chitosan is digested by lysozyme , a human enzyme which is present is tears, saliva and mucus. It breaks down to give glucosamine a sugar already present in the body and helps lubricate joints. Reference (Int. J. Biol. Macromol., 1992, Vol 14 August).